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The 1819 Venture Lab Demo Day highlighted healthcare innovation, featuring startups poised to transform patient care and medical treatment. This event took place at the University of Cincinnati’s 1819 Innovation Hub, reinforcing the region’s status as a leader in health and life sciences.
Entrepreneurs showcased technologies, including concussion prevention equipment, advanced radiation therapy techniques, and improved cardiac arrest response systems. These innovations demonstrate Cincinnati’s commitment to becoming a key player in the healthcare sector. The startups involved represent a tangible shift towards implementing groundbreaking ideas into effective healthcare solutions.
The facts
According to Kate Harmon, assistant vice president of the 1819 Innovation Hub and director of the UC Center for Entrepreneurship, the acceleration of biotech discoveries is crucial for new startups. “We realized that researchers needed a streamlined path to commercialize their findings, prompting us to create an accelerator program specifically aimed at fostering medical innovations,” Harmon stated. This initiative connects researchers with resources to transform concepts into impactful healthcare solutions.
Advancements in diagnostic technologies
A significant challenge in pediatric healthcare is the accurate diagnosis of abdominal pain in children. The startup Appai by Futureheal addresses this issue with a rapid, data-driven analysis tool that leverages insights from 17 million pediatric cases. Rather than relying on slow and often inconclusive tests, Appai offers a cost-effective and efficient diagnostic alternative, currently gaining traction with 24 clients and 97 usage licenses.
Improving emergency response
In emergencies, every second matters. The company corVita has developed a universal AED pad adapter that mitigates critical delays often encountered when switching between different brands of automated external defibrillators (AEDs). The Red Cross emphasizes that survival rates decline by 10% for every minute that CPR and AED use is delayed, underscoring the need for timely intervention. With its innovative design, corVita aims to facilitate quicker access to life-saving devices.
Revolutionizing clinical trials
Another startup making strides is PatientX, which addresses the common issue of clinical trial dropouts. With attrition rates often between 25-30%, PatientX offers a platform that monitors emotional and experiential factors contributing to participant dropout. Founders Jodie Huddleston and Elizabeth Sternke aim to enhance participant satisfaction and retention by providing real-time insights and validated measurement tools.
Precision in cancer treatment
Ensuring accuracy in cancer treatment is critical, particularly with methods like proton radiotherapy, which currently face a 3-5% error margin. Range Assure, founded by professor Jimmy Stringer, has developed a calibration phantom that more accurately mimics real anatomy, significantly lowering the risk of treatment errors. Even minor improvements in targeting accuracy can greatly enhance patient outcomes.
Additionally, Saturn Sports is focused on improving safety in contact sports. With approximately 64 million Americans experiencing at least one traumatic brain injury, the company enhances helmet safety through real-time monitoring of chinstrap tension. Their innovative approach combines helmet-mounted sensors with sideline software, ensuring better protection for athletes.
Innovative sleep apnea solutions
For the 30 million Americans suffering from obstructive sleep apnea, traditional CPAP masks can be uncomfortable. The startup VortexPAP, co-founded by Varun Kalairasan and research professor Liran Oren, is transforming treatment with a system that uses pulsating airflow to maintain airway support without the discomfort of conventional masks. Their goal is to simplify the treatment process, making adherence easier for patients.
The momentum surrounding healthcare innovation in Cincinnati is evident, with the 1819 Innovation Hub serving as a crucial resource for startups aiming to make an impact. The ongoing collaboration between researchers and entrepreneurs is essential for turning innovative ideas into practical healthcare solutions that will shape the future.

